The Agilent 6470 triple quadrupole LC-MS has been engineered to be the company’s most robust triple quadrupole systems, providing attogram-level sensitivity and accurate quantitation with up to six orders of linear dynamic range. It includes built-in Jet Stream technology, which provides 5× the sensitivity of traditional electrospray ionisation; enhanced Q1 ion optics with optimised prefilter geometry, which increase ion transmission to reduce contamination; a tapered hexapole collision cell; an ion detector with a high-energy conversion dynode and low noise characteristics; and MassHunter data handling software.